Article
Molecular diagnostic tools for the World Health Organization (WHO) 2021 classification of gliomas, glioneuronal and neuronal tumors; an EANO guideline.
Neuro-oncology - 3 Oct 2023
Sahm Felix, Brandner Sebastian, Bertero Luca, Capper David, French Pim J, Figarella-Branger Dominique, Giangaspero Felice, Haberler Christine, Hegi Monika E, Kristensen Bjarne W, Kurian Kathreena M, Preusser Matthias, Tops Bastiaan B J, van den Bent Martin, Wick Wolfgang, Reifenberger Guido, Wesseling Pieter
Abstract excerpt
In the 5th edition of the WHO CNS tumor classification (CNS5, 2021), multiple molecular characteristics became essential diagnostic criteria for many additional CNS tumor types. For those tumors, an integrated, "histomolecular" diagnosis is required. A variety of approaches exists for determining the status of the underlying molecular markers. The present guideline focuses on the methods that can be used for...
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