Article
Targeted next-generation sequencing of adult gliomas for retrospective prognostic evaluation and up-front diagnostics.
Neuropathology and applied neurobiology - 1 Feb 2021
Petersen J K, Boldt H B, Sørensen M D, Blach S, Dahlrot R H, Hansen S, Burton M, Thomassen M, Kruse T, Poulsen F R, Andreasen L, Hager H, Ulhøi B P, Lukacova S, Reifenberger G, Kristensen B W
Abstract excerpt
AIMS: We aimed to reclassify a population-based cohort of 529 adult glioma patients to evaluate the prognostic impact of the 2016 World Health Organization (WHO) central nervous system tumour classification. Moreover, we evaluated the feasibility of gene panel next-generation sequencing (NGS) in daily diagnostics of 225 prospective glioma patients. METHODS: The retrospective cohort was reclassified according to...
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