Whole-exome sequencing analysis identifies novel variants associated with Kawasaki disease susceptibility

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Kawasaki disease (KD) is an acute pediatric vasculitis affecting genetically susceptible infants and children. Although the pathogenesis of KD remains unclear, growing evidence links genetic susceptibility to the disease. To explore the genes associated with susceptibility in KD, we conducted whole-exome sequencing of KD children from Yunnan province, China. <bo...

Topics

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• Child
• China
• Exome Sequencing
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Infant
• Mucocutaneous Lymph Node Syndrome
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

675b73c6-e93d-52c8-97c1-3058f74dd726

DOI

10.21203/rs.3.rs-2272385/v1