Article
Whole-Exome Sequencing for Identification of Potential Sex-Biased Variants in Kawasaki Disease Patients.
Inflammation - 1 Dec 2023
Xu Yufen, Che Di, Zuo Xiaoyu, Fu Lanyan, Pi Lei, Zhou Huazhong, Tan Yaqian, Wang Kejian, Gu Xiaoqiong
Abstract excerpt
Kawasaki disease (KD) is an autoimmune disease of unknown etiology and has become a main cause of childhood acquired heart disease. KD is more prevalent in males than in females. The reason for this sex bias is unknown. Here, we used whole-exome sequencing (WES) to identify significantly different variants between male and female KD patients. From WES result, a total of 19,500 shared genetic variants in 8421...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.