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Clinical application of immunogenic cell death inducers in cancer immunotherapy: turning cold tumors hot

7 May 2024

Abstract excerpt

Immunotherapy has emerged as a promising cancer treatment option in recent years. In immune "hot" tumors, characterized by abundant immune cell infiltration, immunotherapy can improve patients' prognosis by activating the function of immune cells. By contrast, immune "cold" tumors are often less sensitive to immunotherapy owing to low immunogenicity of tumor cells, an immune inhibitory tumor microenvironment, and...

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PMID: 38774648
DOI: 10.3389/fcell.2024.1363121

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