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Local Delivery of Accutox® Synergises With Immune-checkpoint Inhibitors at Disrupting Tumor Growth

2024-02-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The Accum® platform was initially designed to accumulate biomedicines in target cells by inducing endosomal-to-cytosol escape. Interestingly however, the use of unconjugated Accum® was observed to trigger cell death in a variety of cancer cell lines; a property that was further exploited in the development of Accum®-based anti-cancer therapies. Despite the impre...

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Literature Corpus work
f82c28c0-a6f0-54b6-a020-af755941fafb
DOI
10.21203/rs.3.rs-3950210/v1
Open publication

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Local Delivery of Accutox® Synergises With Immune-checkpoint Inhibitors at Disrupting Tumor GrowthDOI 10.21203/rs.3.rs-3950210/v1
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