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Association of loneliness, social isolation, and neuroticism in Alzheimer’s disease risk:  a two-step Mendelian randomization study

2024-06-18

Abstract excerpt

<title>Abstract</title> <p>Alzheimer's disease (AD) is a significant global health concern, yet psychosocial factors and human behaviours with the potential to influence genetic factors and dementia risk remain largely underexplored. We employed a two-sample Mendelian randomization (MR) approach to investigate the causality of genetically determined loneliness and social isolation in neuropsychiatric symptoms and...

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Literature Corpus work
6747c304-db8c-59ae-97d5-84449a4e963c
DOI
10.21203/rs.3.rs-4351073/v1
Open publication

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Association of loneliness, social isolation, and neuroticism in Alzheimer’s disease risk: a two-step Mendelian randomization studyDOI 10.21203/rs.3.rs-4351073/v1
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