Article
Social Isolation, Social Interaction, and Alzheimer's Disease: A Mendelian Randomization Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2021
Shen Ling-Xiao, Yang Yu-Xiang, Kuo Kevin, Li Hong-Qi, Chen Shi-Dong, Chen Ke-Liang, Dong Qiang, Tan Lan, Yu Jin-Tai
Abstract excerpt
BACKGROUND: Social isolation and social interaction have been suggested to be associated with Alzheimer's disease. However, the causality cannot be unambiguously assessed as traditional epidemiological methods are easily subject to unmeasured confounders and potential bias. OBJECTIVE: To examine bidirectional relationships between social isolation, social interaction, and Alzheimer's disease using Mendelian...
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