Article
Polysocial and Polygenic Risk Scores and All-Cause Dementia, Alzheimer’s Disease, and Vascular Dementia
14 Nov 2023
Abstract excerpt
BACKGROUND: To establish a polysocial risk score (PsRS) incorporating various social factors for capturing the dementia risk and investigate the benefits of favorable social conditions across different genetic backgrounds. METHODS: This prospective cohort study comprised 345 439 participants initially free of dementia from the UK Biobank. A total of 10 social factors were summed to create a PsRS. A polygenic risk...
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