Back to search

Article

A ω-secalin contained decamer shows a celiac disease prevention activity

2012-03-01

Abstract excerpt

Celiac disease (CD) is an autoimmune permanent enteropathy that is triggered in susceptible individuals after the ingestion of gluten, a storage protein fraction presents in wheat, rye and barley endosperm. Specific gluten peptides can bind to HLA-DQ2/8 and induce lamina propria CD4⁺ T cell responses causing damage of the small intestine mucosa. Recent studies suggested that beside immunodominant and toxic epitope...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6733765a-10d8-5c0b-b960-bda855f2129e
DOI
10.1016/j.jcs.2011.12.006
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A ω-secalin contained decamer shows a celiac disease prevention activityDOI 10.1016/j.jcs.2011.12.006
Toxic, Immunostimulatory and Antagonist Gluten Peptides in Celiac DiseaseSemantic proximity
A catalogue of Triticum monococcum genes encoding toxic and immunogenic peptides for celiac disease patientsSemantic proximity
A monoclonal antibody that recognizes a potential coeliac-toxic repetitive pentapeptide epitope in gliadinsSemantic proximity
Celiac disease and cereal proteinsSemantic proximity
Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops SpeciesSemantic proximity
A universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac disease.Semantic proximity
Oats as a Safe Alternative to Triticeae Cereals for People Sufferring from Celiac Disease?Semantic proximity
Evaluation of alpha-gliadin celiac disease epitopes in some Aegilops species containing the D genome.Semantic proximity
Next-generation therapies for celiac disease: The gluten-targeted approachesSemantic proximity
Celiac disease: from pathogenesis to novel therapies.Semantic proximity
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue.Semantic proximity
Diversification of the celiac disease α‐gliadin complex in wheat: a 33‐mer peptide with six overlapping epitopes, evolved following polyploidizationSemantic proximity
Select a neighboring publication to make it the new centre.