Article
A universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac disease.
PloS one - 16 Dec 2010
Mitea Cristina, Salentijn Elma M J, van Veelen Peter, Goryunova Svetlana V, van der Meer Ingrid M, van den Broeck Hetty C, Mujico Jorge R, Montserrat Veronica, Monserrat Veronica, Gilissen Luud J W J, Drijfhout Jan Wouter, Dekking Liesbeth, Koning Frits, Smulders Marinus J M
Abstract excerpt
Celiac disease is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins, including the α-gliadins. It has been shown that α-gliadins harbor several major epitopes involved in the disease pathogenesis. A major step towards elimination of gluten toxi...
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