Article

Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes

2017-01-12

Abstract excerpt

<h4>ABSTRACT</h4> Over 95% of human multi-exon genes undergo alternative splicing, a process important in normal development and often dysregulated in disease. We sought to analyze the global splicing regulatory network of CELF2 in human T cells, a well-studied splicing regulator critical to T cell development and function. By integrating high-throughput sequencing data for binding and splicing quantification wit...

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Literature Corpus work: 672d3d0a-5219-56da-ba2a-f8f728f8f644
DOI: 10.1101/099853

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