Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans

23 Nov 2022

Abstract excerpt

The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO 2 concentrations has only recently been considered an important virulence trait. Through screening gene knockout libraries constructed in a CO 2 -tolerant clinical strain, we found mutations leading to CO 2 sensitivity are enriched in pathways activated by heat stress, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Plant Pathogens and Fungal Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36416414
DOI: 10.7554/elife.82563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformansPMID 36416414Read ↗

The RAM signaling pathway links morphology, thermotolerance, and CO <sub>2</sub> tolerance in the global fungal pathogen <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

The COMPASS Complex Regulates Fungal Development and Virulence through Histone Crosstalk in the Fungal Pathogen Cryptococcus neoformansSemantic proximity Read ↗

Phenotypic landscape of a fungal meningitis pathogen reveals its unique biologySemantic proximity Read ↗

Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetrySemantic proximity Read ↗

Conserved Elements of the RAM Signaling Pathway Establish Cell Polarity in the Basidiomycete<i>Cryptococcus neoformans</i>in a Divergent Fashion from Other FungiSemantic proximity Read ↗

Discovery of CO2 tolerance genes associated with virulence in the fungal pathogen Cryptococcus neoformansSemantic proximity Read ↗

The interactome of <i>Cryptococcus neoformans</i> Rmt5 reveals multiple regulatory points in fungal cell biology and pathogenesisSemantic proximity Read ↗

<i>Cryptococcus neoformans</i> adapts to host CO <sub>2</sub> concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasisSemantic proximity Read ↗

Thermoregulation network governing virulence of a critical human fungal pathogenSemantic proximity Read ↗

Microevolution of Cryptococcus neoformans in high CO2 converges on mutations isolated from patients with relapsed cryptococcosis.Semantic proximity Read ↗

Phenotypic landscape of an invasive fungal pathogen reveals its unique biology.Semantic proximity Read ↗

Calcineurin controls the cytokinesis machinery during thermal stress in <i>Cryptococcus deneoformans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.