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Host carbon dioxide concentration is an independent stress for <i>Cryptococcus neoformans</i> that affects virulence and antifungal susceptibility

2019-06-04

Abstract excerpt

The ability of Cryptococcus neoformans to cause disease in humans varies significantly among strains with highly related genotypes. In general, environmental isolates of pathogenic species such as C. neoformans var. grubii have reduced virulence relative to clinical isolates, despite having no differences in the expression of the canonical virulence traits (high temperature growth, melanization and capsule form...

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Literature Corpus work
7fce0709-a616-517e-b98d-467ddd047e06
DOI
10.1101/659789
Open publication

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Host carbon dioxide concentration is an independent stress for <i>Cryptococcus neoformans</i> that affects virulence and antifungal susceptibilityDOI 10.1101/659789
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