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Article

The RhoA GTPase regulates Type I Interferon Signaling in Systemic lupus erythematosus

2023-09-20

Abstract excerpt

<h4>Objective: </h4> Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored the role of the RhoA GTPase in the type I IFN activation pathway to provide a potential basis for targeting GTPase signaling for the treatment of SLE. <h4>Methods: </h4>. Total RNA was extrac...

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Literature Corpus work
66f64261-ca18-5ce2-a68c-314a38859f71
DOI
10.21203/rs.3.rs-3320841/v1
Open publication

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The RhoA GTPase regulates Type I Interferon Signaling in Systemic lupus erythematosusDOI 10.21203/rs.3.rs-3320841/v1
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