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Article

Type I Interferons in the Pathogenesis and Treatment of Autoimmune Diseases.

Clinical reviews in allergy & immunology - 1 Oct 2020

Jiang Jiao, Zhao Ming, Chang Christopher, Wu Haijing, Lu Qianjin

Abstract excerpt

Type I interferons (IFN-Is) are a very important group of cytokines that are produced by innate immune cells but also act on adaptive immune cells. IFN-Is possess antiviral, antitumor, and anti-proliferative effects, as well are associated with the initiation and maintenance of autoimmune disorders. Studies have shown that aberrantly expressed IFN-Is and/or type I IFN-inducible gene signatures in the serum or...

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Identifiers

PMID: 32557263
DOI: 10.1007/s12016-020-08798-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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