Article
Association of signaling transducers and activators of transcription 1 and systemic lupus erythematosus.
Autoimmunity - 1 May 2014
Liang Yan, Xu Wang-Dong, Yang Xiao-Ke, Fang Xin-Yu, Liu Yan-Yan, Ni Jing, Qiu Li-Juan, Hui Peng, Cen Han, Leng Rui-Xue, Pan Hai-Feng, Ye Dong-Qing
Abstract excerpt
Systemic lupus erythematosus (SLE) is complex autoimmune disease which involves various facets of the immune system. Signaling transducers and activators of transcription 1 (STAT1) belongs to the family of STAT transcription factors that mediate various biological responses. Recently, studies in both experimental animal models of lupus and patients with SLE have revealed expression and activation of STAT1 is...
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