Article

Retinoblastoma ( Rb ) promotes senescence of corneal endothelial cells by inhibiting the activation of E2F2

2020-05-31

Abstract excerpt

<h4>Background: </h4> Senescence-like changes occur in aging Corneal endothelial cells (CECs), and these changes are associated with decreased vision and age-related corneal diseases. such as Fuchs endothelial dystrophy (FED), chronic corneal allograft dysfunction (CCAD). Such changes have also been shown to cultured cell in vitro after passaging. Therefore, studying the mechanism of CEC senescence would aid in th...

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Literature Corpus work: 66b9008e-c100-5a5e-a4ff-cf3e04e9966b
DOI: 10.21203/rs.3.rs-23760/v1

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