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A case report of SMARCA4/BRG1-deficient non-small cell lung cancer with a spindle cell component found by next-generation sequencing of a brain metastasis

2020-07-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Several studies of different cancers have revealed mutations in switch/sucrose non-fermenting (SWI/SNF) complex genes. Brahma-related gene 1 (BRG1), which is encoded by SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 4 (<italic>SMARCA4</italic>), is a member of this complex. <italic>SMARCA4</italic>/BRG-1-deficient...

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Literature Corpus work
6649b368-a59a-5fcf-bde9-8bb21a07d535
DOI
10.21203/rs.3.rs-45392/v1
Open publication

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