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Article

SMARCA4-Deficient Undifferentiated Tumor of Lung Mass-A Rare Tumor With the Rarer Occurrence of Brain Metastasis: A Case Report and Review of the Literature.

Journal of investigative medicine high impact case reports - 1 Jan 2000

Yadav Ruchi, Sun Lishi, Salyana Muhammad, Eric Minkin, Gotlieb Vladimir, Wang Jen C

Abstract excerpt

Among thoracic tumors, these include subsets of a relatively newly described and yet to be fully characterized tumor entity: SMARCA4-deficient Undifferentiated Tumor (SMARCA4-dUT). Mutations of SMARCA4 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 4) gene and loss of BRG1 (Brahma-related gene-1) is the underlying molecular hallmark of SMARCA4-dUT. They mostly...

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Identifiers

PMID: 35356840
DOI: 10.1177/23247096221074864
PMCID: PMC8978313

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SMARCA4-Deficient Undifferentiated Tumor of Lung Mass-A Rare Tumor With the Rarer Occurrence of Brain Metastasis: A Case Report and Review of the Literature.PMID 35356840Read ↗

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