Article

Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids

2021-09-21

Abstract excerpt

Despite holding great therapeutic potential, existing protocols for in vitro chondrogenesis and hyaline cartilage production from human induced pluripotent stem cells (hiPSC) are laborious and complex with unclear long-term consequences. Here, we developed a simple xeno- and feeder-free protocol for human hyaline cartilage production in vitro using hydrogel-cultured multi-tissue organoids (MTOs). We investigate...

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Literature Corpus work: 662f22a5-e823-5b66-a348-b742e85f8d65
DOI: 10.1101/2021.09.21.461213

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