Article
Craniofacial cartilage organoids from human embryonic stem cells via a neural crest cell intermediate
2021-05-31
Abstract excerpt
Severe birth defects or major injuries to the face require surgical reconstruction and rehabilitation. The ability to make bona fide craniofacial cartilage – cartilage of the head and face – from patient-derived induced pluripotent stem cells (iPSCs) to repair these birth defects and injuries has tremendous translational applications, but is not yet possible. The neural crest is the normal developmental pathway fo...
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Identifiers and source
- Literature Corpus work
- 3cdcc413-48d9-5b01-aa91-113baec63273
- DOI
- 10.1101/2021.05.31.446459