Article

Single-cell sequencing combined with Mendelian randomization to explore the molecular mechanisms related to abdominal aortic aneurysm

2026-05-13

Abstract excerpt

<title>Abstract</title> <p>Abdominal Aortic Aneurysm (AAA) is a life-threatening vascular disorder with high mortality from rupture, lacking effective early diagnostic biomarkers and disease-modifying therapies. To decipher its cell-type-specific molecular mechanisms, this study integrated single-cell RNA sequencing (scRNA-seq) and Mendelian randomization (MR), alongside multiple bioinformatics analyses. We acqui...

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Literature Corpus work: 6629ed5e-1a9c-5b48-8c84-d42790856e12
DOI: 10.21203/rs.3.rs-9531234/v1

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