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Article

Targeted inhibition of CD47 expression in Human cancer cell lines on treatment with Cardiac Glycosides

2022-12-15

Abstract excerpt

<title>Abstract</title> <p>The interest has grown in therapeutically targeting Hypoxia-inducible factor 1α (HIFα), which directly stimulates the expression of cluster of differentiation 47 (CD47) on the cell surface that suppresses phagocytosis in cancer cells. Increased expressions of CD47 and counter interaction with signal regulatory protein alpha (SIRPα) enable cancer cells to avoid cell-mediated cell destruc...

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Literature Corpus work
65e17dec-212f-50a4-bfa9-7105f5c7fd2c
DOI
10.21203/rs.3.rs-2361555/v1
Open publication

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Targeted inhibition of CD47 expression in Human cancer cell lines on treatment with Cardiac GlycosidesDOI 10.21203/rs.3.rs-2361555/v1
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