Article

Identifying drug targets for schizophrenia through gene prioritization

2024-05-16

Abstract excerpt

<h4>Background</h4> Schizophrenia genome-wide association studies (GWASes) have identified >250 significant loci and prioritized >100 disease-related genes. However, gene prioritization efforts have mostly been restricted to locus-based methods that ignore information from the rest of the genome. <h4>Methods</h4> To more accurately characterize genes involved in schizophrenia etiology, we applied a combination of...

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Literature Corpus work: 65c571b5-dd2a-5e35-b052-c615ba556475
DOI: 10.1101/2024.05.15.24307423

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