Article
Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic.
Molecular psychiatry - 1 Jul 2015
Lencz T, Malhotra A K
Abstract excerpt
The Psychiatric Genomics Consortium-Schizophrenia Workgroup (PGC-SCZ) has recently published a genomewide association study (GWAS) identifying >100 genetic loci, encompassing a total of 341 protein-coding genes, attaining genomewide significance for susceptibility to schizophrenia. Given the extremely long time (12-15 years) and expense (>$1 billion) associated with the development of novel drug targets,...
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