Article

Obesity-mediated upregulation of the YAP/IL33 signaling axis promotes an immunosuppressive tumor microenvironment in breast cancer

2022-09-21

Abstract excerpt

Obesity is a well-known risk factor for breast cancer formation and is associated with elevated mortality and a poor prognosis. An obesity-mediated inflammatory microenvironment is conducive to the malignant progression of tumors. However, the detailed molecular mechanism is still needed to be clarified. Herein, we identified that breast cancer cells from mice with diet-induced obesity exhibited increased growth,...

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Literature Corpus work: 65c2f248-f03f-5fea-b879-aab8779be540
DOI: 10.21203/rs.3.rs-2079726/v1

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