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Article

S1PR1/S1PR3-YAP signaling and S1P-ALOX15 signaling contribute to an aggressive behavior in obesity-lymphoma

5 Jan 2023

Abstract excerpt

BACKGROUND: Excess body weight has been found to associate with an increased risk of lymphomas and some metabolic pathways are currently recognized in lymphomagenesis. Bioactive lipid metabolites such as sphingosine-1-phosphate (S1P) have been proposed to play an important role linking obesity and lymphomas. However, the underlying mechanism(s) of S1P signaling in obesity-lymphomagenesis have not been well...

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Adipokines, Inflammation, and Metabolic Diseases
Autophagy in Disease and Therapy
Sphingolipid Metabolism and Signaling

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36600310
DOI: 10.1186/s13046-022-02589-7

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