Article

Metabolically activated macrophages in mammary adipose tissue link obesity to triple-negative breast cancer

2018-07-17

Abstract excerpt

<h4>SUMMARY</h4> Obesity is associated with increased incidence and severity of triple-negative breast cancer (TNBC); however, mechanisms underlying this relationship are incompletely understood. Macrophages, which accumulate in adipose tissue and are activated during obesity, are an attractive mechanistic link. Here, we show that, during obesity, murine and human mammary adipose tissue macrophages adopt a pro-in...

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Literature Corpus work: d434ab95-adcf-5d09-89fa-79512f8f584e
DOI: 10.1101/370627

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