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Interleukin-33: Friend or Foe in Gastrointestinal Tract Cancers?

26 May 2023

Abstract excerpt

Accumulating evidence suggests that Interleukin-33 (IL-33), a member of the IL-1 family, has crucial roles in tissue homeostasis and repair, type 2 immunity, inflammation, and viral infection. IL-33 is a novel contributing factor in tumorigenesis and plays a critical role in regulating angiogenesis and cancer progression in a variety of human cancers. The partially unraveled role of IL-33/ST2 signaling in...

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PMID: 37296602
DOI: 10.3390/cells12111481

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