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Article

Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10.

Journal of molecular endocrinology - 9 Sept 2021

Alhallak Iad, Wolter Keith G, Castro Munoz Ana, Simmen Frank A, Ward Richard J, Petty Stacy A, Li Lin-Xi, Simmen Rosalia C M

Abstract excerpt

Epidemiological studies inversely associate BMI with breast cancer risk in premenopausal women, but the pathophysiological linkage remains ill-defined. Despite the documented relevance of the 'local' environment to breast cancer progression and the well-accepted differences in transcriptome and metabolic properties of anatomically distinct fat depots, specific breast adipose contributions to the proliferative...

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Source

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Identifiers

PMID: 34382943
DOI: 10.1530/JME-21-0100
PMCID: PMC8489570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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