Article

Role of acetoacetyl-CoA synthetase in glucose uptake by HepG2 cells

2023-02-04

Abstract excerpt

Accelerated glucose metabolism is a common feature of cancer cells and represents a potential therapeutic target. Recent studies have revealed that lipid metabolism is related to glucose me-tabolism, especially glucose uptake. Acetoacetyl-CoA synthetase (AACS) converts acetoacetate, a ketone body, to acetoacetyl-CoA, which is incorporated into cholesterol and fatty acids. The AACS gene is highly expressed in HepG2...

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Literature Corpus work: 659f35a8-88d8-5415-9e5f-4e2ae8bcd143
DOI: 10.1101/2023.02.04.527056

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