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Article

Glucose-stimulated upregulation of GLUT2 gene is mediated by sterol response element-binding protein-1c in the hepatocytes.

Diabetes - 1 Jun 2005

Im Seung-Soon, Kang Seung-Youn, Kim So-Youn, Kim Ha-Il, Kim Jae-Woo, Kim Kyung-Sup, Ahn Yong-Ho

Abstract excerpt

GLUT2 is mainly expressed in the liver, beta-cells of the pancreas, and the basolateral membrane of kidney proximal tubules and plays an important role in glucose homeostasis in living organisms. The transcription of the GLUT2 gene is known to be upregulated in the liver during postprandial hyperglycemic states or in type 2 diabetes. However, a molecular mechanism by which glucose activates GLUT2 gene expression...

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Identifiers

PMID: 15919789
DOI: 10.2337/diabetes.54.6.1684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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