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Article

Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis.

Cancer medicine - 1 Apr 2018

Kuang Ye, Han Xiaoyun, Xu Mu, Yang Qing

Abstract excerpt

Most cancer cells perform glycolysis despite having sufficient oxygen. The specific metabolic pathways of cancer cells have become the focus of cancer treatment. Recently, accumulating evidence indicates oxidative phosphorylation (OXPHOS) and glycolysis can be regulated with each other. Thus, we suggest that the glycolysis of cancer cells is inhibited by restoring or improving OXPHOS in cancer cells. In our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29533007
DOI: 10.1002/cam4.1410
PMCID: PMC5911603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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