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Article

Interleukin-33 Promotes Cell Survival via P38 MAPK-mediated Interleukin-6 Gene Expression and Release in Pediatric AML

2020-08-17

Abstract excerpt

<title>Abstract</title> <p>BackgroundAcute myeloid leukemia (AML) is a fatal disease characterized by an accumulation of immature myeloid blasts in the bone marrow (BM). Cytokine provide signals for leukemia cell to better survive in the BM microenvironment. Previously, we identified interleukin-33 (IL-33) as a stimulator of cell survival in human AML cell line and primary mouse leukemia cells. However, the mecha...

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Literature Corpus work
0ca20fee-7209-512c-b9d6-cdf31020f606
DOI
10.21203/rs.3.rs-59371/v1
Open publication

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Interleukin-33 Promotes Cell Survival via P38 MAPK-mediated Interleukin-6 Gene Expression and Release in Pediatric AMLDOI 10.21203/rs.3.rs-59371/v1
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