Article

Understanding functional mechanisms of genetic susceptibility to mycobacterial infection

2018-01-01

Abstract excerpt

Tuberculosis remains a major public health problem and one of the leading causes of death worldwide. Human genetic factors determine susceptibility to M. tuberculosis (M. tb) infection and predispose to clinical TB. Genome-wide association studies (GWAS) aim to discover human genes associated with susceptibility to TB. Recently, a GWAS conducted by our lab identified a new TB-associated gene ASAP1 that encodes an...

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Literature Corpus work: 657063ed-86f0-5e59-a71c-d8d3c1a737b3
DOI: 10.17863/cam.25239

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