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Research progress on genetic control of host susceptibility to tuberculosis.

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 25 Dec 2022

Hu Wenjuan, Xu Kaijin

Abstract excerpt

The "Lübeck disaster", twins studies, adoptees studies, and other epidemiological observational studies have shown that host genetic factors play a significant role in determining the host susceptibility to Mycobacterium tuberculosis infection and pathogenesis of tuberculosis. From linkage analyses to genome-wide association studies, it has been discovered that human leucocyte antigen (HLA) genes as well as...

Topics

Humans
Genome-Wide Association Study
Tuberculosis
Gene Expression Regulation
Cytokines
Autoimmune Diseases
Mycobacterium tuberculosis
Genetic Predisposition to Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36915969
DOI: 10.3724/zdxbyxb-2022-0484
PMCID: PMC10262011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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