Article
Molecular immunity to mycobacteria: knowledge from the mutation and phenotype spectrum analysis of Mendelian susceptibility to mycobacterial diseases.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 May 2011
Qu Hui-Qi, Fisher-Hoch Susan P, McCormick Joseph B
Abstract excerpt
Understanding molecular immunity against mycobacterial infection is critical for the development of effective strategies to control tuberculosis (TB), which is a major health issue in the developing world. Host immunogenetic studies represent an indispensable approach to understand the molecular mechanisms against mycobacterial infection. A superb paradigm is the identification of rare mutations causing Mendelian...
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