Article
Genetic determinants of susceptibility to Mycobacterial infections: IRF8, a new kid on the block.
Advances in experimental medicine and biology - 1 Jan 2013
Salem S, Gros P
Abstract excerpt
Genetic and population studies suggest that onset, progression and ultimate outcome of infection with Mycobacteria, including the agent of tuberculosis Mycobacterium tuberculosis, are strongly influenced by genetic factors. Family-based and case-control linkage and association studies have suggested a complex genetic component for susceptibility to tuberculosis. On the other hand, patients with inborn errors in...
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