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Article

ASAP1 as a novel dual-level biomarker for tuberculosis: integrated genetic and proteomic evidence for early detection and disease monitoring.

Molecular biology reports - 2 Feb 2026

Shahzad Faheem, Jahan Shah, Rathore Ahsan Waheed, Ain Fasihat Ul, Ali Atia, Kashif Mohammad, Ammar Ali, Tahir Romeeza, Afzal Nadeem

Abstract excerpt

BACKGROUND: Tuberculosis (TB) remains a major global health challenge, with limitations in current diagnostics prompting interest in host-derived biomarkers. This study evaluated the role of ASAP1, a regulator of actin cytoskeleton remodeling and dendritic cell migration, as a genetic and molecular biomarker for TB. A case–control cohort comprising 164 TB patients and 85 healthy controls was analyzed for two...

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PMID: 41627576
DOI: 10.1007/s11033-026-11507-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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