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Age but not disease progression defines CD4 <sup>+</sup> and CD8 <sup>+</sup> T stem cell memory levels in human retroviral infections: contrasting effects of HTLV-1 and HIV-1

2018-11-19

Abstract excerpt

<h4>Background</h4> Human CD4 + and CD8 + stem cell memory T cells (T SCM ) represent a minor fraction of circulating lymphocytes characterized by stemness and long-term in vivo persistence. CD4 + T SCM are preferentially infected and constitute a reservoir for HIV-1, whereas CD8 + T SCM appear to play a protective role. However, little is known about CD4 + and CD8 + T SCM in the only other human patho...

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Literature Corpus work
656edd34-9758-5d4e-b176-625ed69b5350
DOI
10.1101/473363
Open publication

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Age but not disease progression defines CD4 <sup>+</sup> and CD8 <sup>+</sup> T stem cell memory levels in human retroviral infections: contrasting effects of HTLV-1 and HIV-1DOI 10.1101/473363
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