Article

Phage detection by a bacterial NLR-related protein is mediated by DnaJ

2024-06-04

Abstract excerpt

Bacteria encode a wide range of antiphage systems and a subset of these proteins are homologous to components of the human innate immune system. Mammalian nucleotide-binding and leucine-rich repeat containing proteins (NLRs) and bacterial NLR-related proteins use a central NACHT domain to link detection of infection with initiation of an antimicrobial response. Bacterial NACHT proteins provide defense against both...

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Literature Corpus work: 6539a2e2-09ad-5e6b-8b02-c682ac9f6f2c
DOI: 10.1101/2024.06.04.597415

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