Article
Human Elp3/Kat9 is a mitochondrial tRNA modifying enzyme
2022-03-24
Abstract excerpt
Post-translational modifications, such as lysine acetylation, regulate the activity of diverse proteins across many cellular compartments. Protein deacetylation in mitochondria is catalyzed by the enzymatic activity of the NAD+-dependent deacetylase sirtuin 3 (SIRT3), however it remains unclear whether corresponding mitochondrial acetyltransferases exist. We used a bioinformatics approach to search for mitochondri...
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Identifiers and source
- Literature Corpus work
- 6532b013-651d-520a-ba5c-a11efb29710a
- DOI
- 10.1101/2022.03.24.485634
