Article

SF3A2 deacetylation at lysin 10 mitigates myocardial pathological remodeling by reprogramming cardiomyocyte metabolism

2025-12-27

Abstract excerpt

<h4>Background</h4> Dysregulation of splicing factor-mediated pre-mRNA alternative splicing (AS) underlies the progression of complex diseases, but the specific involvement of AS in myocardial pathological remodeling remains unclear. This study aimed to elucidate the role of splicing factor 3A, subunit 2 (SF3A2) in the development of myocardial pathological remodeling by regulating AS and its effect on metabolic...

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Literature Corpus work: 1822b315-2348-5680-9c48-ebfcf5f9ceb5
DOI: 10.64898/2025.12.26.696635

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