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Article

Exploratory genome-wide analyses of cortical inhibition, facilitation, and plasticity in late-life depression.

Translational psychiatry - 30 Jun 2023

Wathra Rafae A, Men Xiaoyu, Elsheikh Samar S M, Marshe Victoria S, Rajji Tarek K, Lissemore Jennifer I, Mulsant Benoit H, Karp Jordan F, Reynolds Charles F, Lenze Eric J, Daskalakis Zafiris J, Müller Daniel J, Blumberger Daniel M

Abstract excerpt

Late-life depression (LLD) is a heterogenous mood disorder influenced by genetic factors. Cortical physiological processes such as cortical inhibition, facilitation, and plasticity may be markers of illness that are more strongly associated with genetic factors than the clinical phenotype. Thus, exploring the relationship between genetic factors and these physiological processes may help to characterize the...

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PMID: 37391420
DOI: 10.1038/s41398-023-02532-0
PMCID: PMC10313655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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