Article

Migraine pathophysiology : NR2A/SFKs signaling in cortical spreading depression

2017-01-01

Abstract excerpt

Cortical spreading depression (CSD) is a propagating neuronal/glial excitation, followed by depression in cerebral cortex and subcortical regions. It is known to be the underlying cause of migraine with aura in humans. CSD can also lead to migraine-like behavior by triggering pannexin1 (Panx1) channels opening and induce the release of calcitonin gene-related peptide (CGRP) that plays a key player in migraine pati...

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Literature Corpus work: 2d970840-6380-5605-8e04-96165972e332
DOI: 10.17638/03007920

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