Article
Signaling pathway mechanisms of neurological diseases induced by G protein‐coupled receptor 39
21 Mar 2023
Abstract excerpt
BACKGROUND: G protein-coupled receptor 39 (GPR39) is a transmembrane zinc receptor with two splice variants, which belongs to the G-protein-coupled receptor growth hormone-releasing peptide family. Its expression is induced by zinc, which activates GPR39, and its activation mediates cell proliferation, ion homeostasis, and anti-inflammatory, antioxidant, and other pathophysiological effects via different...
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