Article

LFA-1 Knockout Leads to CD4 + and CD8 + T Cells Differentiation Disorder in Thymus Gland and is Related with ERK Signaling Pathway in Mice

2024-05-10

Abstract excerpt

<title>Abstract</title>T cell precursors from fetal liver bone marrow migrate into the thymus to initiate their development, including double-negative selection, double-positive selection, and single-positive selection. Subsequently, fully matured single-positive CD4+T cells or CD8+T cells traverse the bloodstream to the peripheral tissues, executing immune functions. Lymphocyte function-a...

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Literature Corpus work: 6499803d-edd4-5f26-b53b-f9cb29828998
DOI: 10.21203/rs.3.rs-4337853/v1

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