Article

Multi-omic profiling of human thymic B cells reveals intrathymic Ig-class switching and differentiation into multiple memory B cell subsets

2026-05-26

Abstract excerpt

Primarily recognized as the site for T cell development, the thymus supports a complex interplay between thymic stromal cells and developing thymocytes, which is essential for T cell maturation and the establishment of central tolerance. Emerging evidence indicates that thymic B cells contribute to tolerance induction by functioning as antigen-presenting cells. However, their developmental pathways and functional...

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Literature Corpus work: 9658f869-0dbb-5ce8-8ead-7bec5b42976c
DOI: 10.64898/2026.05.21.725517

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