Article

The Mechanism of Vascular Endothelial Dysfunction Induced by Ferroptosis Mediated by NARFL Knockout

2024-02-08

Abstract excerpt

<h4>BACKGROUND</h4> Nuclear prelamin A recognition factor-like (NARFL) plays a crucial role in cytosolic iron-sulfur protein assembly (CIA) and protects cells against oxidative stress. In our previous study, we identified a novel homozygous mutation in NARFL that led to decreased expression in a consanguineous family with diffuse pulmonary arteriovenous malformations (DPAVMs) secondary to pulmonary hypertension. A...

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Literature Corpus work: 648dcf3b-ef58-50b2-9028-6eb9961362b3
DOI: 10.1101/2024.02.06.24302421

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